2-Chloro-N-(4-sulfamoylphenyl)acetamide
نویسندگان
چکیده
In the title compound, C(8)H(9)ClN(2)O(3)S, the benzene ring makes a dihedral angle of 4.1 (9)° with the amido -NHCO- plane including the major occupancy component of the carbonyl O atom [19 (4)° for the minor component]. An intra-molecular C-H⋯O inter-action occurs. The O atom of the carbonyl group is disordered over two positions with site-occupancy factors of 0.67 (11) and 0.33 (11). Inter-molecular N-H⋯O hydrogen bonds help to stabilize the crystal structure.
منابع مشابه
N-(4-Sulfamoylphenyl)acetamide
In the title compound, C(8)H(10)N(2)O(3)S, the dihedral angle between the acetamide group and the benzene ring is 15.59 (12)° and the amino group is close to being perpendicular to the benzene ring [N-S-C(ar)-C(ar) (ar = aromatic) torsion angle = 109.4 (2)°]. In the crystal, mol-ecules are linked into supra-molecular tubes parallel to [001] by amine-amide N-H⋯O inter-actions and these are conne...
متن کامل2-Chloro-N-(3-methylphenyl)acetamide
The conformation of the N-H bond in the structure of the title compound, C(9)H(10)ClNO, is syn to the meta-methyl group, in contrast to the anti conformation observed with respect to the meta-nitro group in 2-chloro-N-(3-nitro-phen-yl)-acetamide. The asymmetric unit of the title compound contains two mol-ecules. The geometric parameters of the title compound are similar to those of 2-chloro-N-(...
متن کاملN-Benzyl-2-(3-chloro-4-hydroxyphenyl)acetamide
The title compound, C(15)H(14)ClNO(2), was synthesized as part of a project to generate a combinatorial library based on the fungal natural product 2-(3-chloro-4-hy-droxy-phen-yl)acetamide. It crystallizes as non-planar discrete mol-ecules [the peripheral 3-chloro-4-hy-droxy-phenyl and benzyl groups are twisted out of the plane of the central acetamide group, with N-C-C-C and C-C-C-C torsion an...
متن کاملSynthesis, characterization and antimicrobial evaluation of novel imines and thiazolidinones.
2-(4-Chloro-3-methylphenoxy)acetohydrazide (2) derived from ethyl 2-(4-chloro-3-methylphenoxy) acetate (1) was reacted with different aromatic aldehydes to yield N-(substituted benzylidiene)-2-(4-chloro-3-methylphenoxy)acetamide (3a-e). Cyclization of compound (3a-e) with thioglycolic acid yielded 2-(4-chloro-3-methylphenoxy)-N-(4-oxo-2-arylthiazolidin-3-yl) acetamide (4a-e). The newly synthesi...
متن کامل2-(3-Chloro-4-hydroxyphenyl)-N-(3,4-dimethoxyphenethyl)acetamide
The title compound, C(18)H(20)ClNO(4), was synthesized during the generation of a combinatorial library based on the fungal natural product 3-chloro-4-hydroxy-phenyl-acetamide. It crystallizes as discrete mol-ecules linked by inter-molecular C(9) chains of N-H⋯O and O-H⋯O hydrogen bonds which in turn combine to form chains of R(2) (2)(20) rings.
متن کامل